From Chemical Menopause to Hysterectomy: Life After PMDD After 18 months on a chemical menopause and HRT, I reached a point where things just weren’t working anymore. My three-monthly injection wasn’t lasting the full cycle—I could feel the effects of PMDD creeping back in at 10 weeks, leaving me with two to three weeks of depression, anxiety, sadness, and exhaustion. It felt like I was back to square one. I started questioning whether my HRT was right, but my GP wasn’t givin